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Online biochemical detection of glutathione-S-transferase P1-specific inhibitors in complex mixtures

Authors :
Kool, Jeroen
Eggink, Mark
Van Rossum, Huub
Van Liempd, Sebastiaan M.
Van Elswijk, Danny A.
Irth, Hubertus
Commandeur, Jan N.M.
Meerman, John H.N.
Vermeulen, Nico P.E.
Source :
Journal of Biomolecular Screening. April 2007, Vol. 12 Issue 3, p396, 10 p.
Publication Year :
2007

Abstract

A high-resolution screening (HRS) technology is described, which couples 2 parallel enzyme affinity detection (EAD) systems for substrates and inhibitors of rat cytosolic glutathione-S-transferases (cGSTs) and purified human GST P1 [...]

Details

Language :
English
ISSN :
10870571
Volume :
12
Issue :
3
Database :
Gale General OneFile
Journal :
Journal of Biomolecular Screening
Publication Type :
Academic Journal
Accession number :
edsgcl.161645837