Structural approach to a novel tandem repeat DNA-building domain, STPR, by CD and NMR

The study employs techniques like NMR and CD calculations to describe the three-dimensional structures of the four tandem repeats of the fibroin-modular-binding protein (FMBP-1), which act as the DNA-binding domain. The analysis shows that the binding of the full-length score and three amino acid peptide repeat leads to an increase in the [alpha]-helicity of the protein regions, which then tend to form a regular secondary structure.