Butenolide synthesis by molybdenum-mediated hetero-Pauson-Khand reaction of alkynyl aldehydes

Authors :: Adrio, Javier
Carretero, Juan C.
Source :: Journal of the American Chemical Society. Jan 31, 2007, Vol. 129 Issue 4, 778-779
Publication Year :: 2007
Abstract: A mild and general CO gas-free procedure is described for the synthesis of fused [alpha],[beta]-butenolides by the hetero-Pauson-Khand reaction (PKR) of alkynyl aldehydes. The exposure of the enantiomerically pure aldehyde to the usual Mo-mediated reaction conditions afforded the butenolide with complete exo selectivity.

Subjects :: Butylene -- Chemical properties
Butylene -- Structure
Molybdenum -- Chemical properties
Molybdenum -- Structure
Chemistry

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