Indication for initiation of mechanical circulatory support impacts survival of infants with shunted single-ventricle circulation supported with extracorporeal membrane oxygenation

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jtcvs.2006.11.013 Byline: Catherine K. Allan (a), Ravi R. Thiagarajan (a), Pedro J. del Nido (b), Stephen J. Roth (c), Melvin C. Almodovar (a), Peter C. Laussen (a) Abbreviations: BT, Blalock-Taussig; CICU, cardiac intensive care unit; CPB, cardiopulmonary bypass; CPR, cardiopulmonary resuscitation; ECMO, extracorporeal membrane oxygenation; ELSO, Extracorporeal Life Support Organization; HLHS, hypoplastic left heart syndrome; IVS, intact ventricular septum; PA, pulmonary atresia; RVDCC, right ventricle-dependent coronary circulation Abstract: The use of extracorporeal membrane oxygenation to support patients with shunted single-ventricle physiology has been controversial. Variable survivals are reported in a number of small case series. We sought to evaluate outcomes and identify predictors of survival for patients with shunted single-ventricle physiology who require extracorporeal membrane oxygenation support. Author Affiliation: (a) Department of Cardiology, Children's Hospital Boston and Harvard Medical School, Boston, Mass (b) Department of Cardiac Surgery, Children's Hospital Boston and Harvard Medical School, Boston, Mass (c) Division of Pediatric Cardiology, Lucile Packard Children's Hospital and Stanford University School of Medicine, Palo Alto, Calif. Article History: Received 24 August 2006; Revised 26 October 2006; Accepted 1 November 2006