Sensitivity and specificity of tests for ocular and oral involvement in Sjogren's syndrome

Tests that detect abnormalities in the eye and salivary glands are the most reliable tools for diagnosing Sjogren's Syndrome. Sjogren's Syndrome refers to a group of symptoms that are sometimes associated with rheumatoid arthritis and systemic lupus erythematosus. Common symptoms include dry mouth, dry eyes and enlarged parotid glands. An analysis of the diagnostic accuracy of various tests revealed that Schirmer's-I-test (ScT) and rose Bengal score (RBS) were the most accurate tests for evaluating symptoms in the eye related to Sjogren's. Salivary gland scintigraphy (SGS), parotid sialography (PS), minor salivary gland biopsy (MSGB), and unstimulated whole saliva collection (UWSC) were the most accurate tests for the oral symptoms.