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Greening Wittig reactions: Solvent-free synthesis of ethyl trans-cinnamate and trans-3-(9-anthryl)-2-propenoic acid ethyl ester

Authors :
Kim Chi Nguyen
Weizman, Haim
Source :
Journal of Chemical Education. Jan, 2007, Vol. 84 Issue 1, 119-121
Publication Year :
2007

Abstract

Green procedure is used to create solvent-free alternatives for conventional Wittig reactions, which are widely used to install a double bond in a highly selective manner. Solvent-free reactions reduce health and environmental risks and provide a basis for an inquiry-based discussion of the stereochemistry of the Wittig reaction and the factors influencing the chemical shifts of alkenyl protons.

Details

Language :
English
ISSN :
00219584
Volume :
84
Issue :
1
Database :
Gale General OneFile
Journal :
Journal of Chemical Education
Publication Type :
Academic Journal
Accession number :
edsgcl.158005291