A common haplotype of the glucokinase gene alters fasting glucose and birth weight: Association in six studies and population-genetics analyses

The role of variation of glucokinase (GCK) in the determination of fasting glucose and birth weight is examined using a tagging single-nucleotide polymorphism (tSNP) approach. A comprehensive analysis of common variation of the glucokinase gene has indicated that this is the first gene to be reproducibly associated with fasting glucose and fetal growth.