Classical molecular electrostatics: Recognition of ligands in proteins and the vibrational stark effect

A study shows that classical electrostatistics describes the quantitative description of, both the binding of the diatomic ligands XO (X= C. N, O) to the heme group in myoglobin and the dependence of their vibrational frequencies upon an external field by classical electrolysis. It is suggested that ligand binding occurs via an electrostatic bond, a generalization of the standard ionic bond to include induction, and that classical electrostatics can replace quantum mechanics for a considerable simplification of some complex problems.