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DNA-dependent ATPase from HeLa cells is related to human Ku autoantigen

Authors :
Cao, Qiu Ping
Pitt, Sidney
Leszyk, John
Baril, Earl F.
Source :
Biochemistry. July 19, 1994, Vol. 33 Issue 28, p8548, 10 p.
Publication Year :
1994

Abstract

The DNA-ATPase purified to homogeneity from the complex of enzymes for DNA synthesis is identical to human Ku autoantigen in that they both are heterodimeric proteins and show 100% similarity in the amino acid sequences of their subunits. The catalytic activity of purified DNA-ATPase/Ku protein is upregulated by phosphorylation due to interaction with DNA dependent protein kinase.

Details

ISSN :
00062960
Volume :
33
Issue :
28
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.15674303