Mechanical control of enantioselectivity of amino acid recognition by cholesterol-armed cyclen monolayer at the air-water interface

An excellently designed polycholesteryl substituted cyclen complex host molecule was employed and the successful inversion of enantioslectivity in molecular recognition controlled by lateral pressure applied to the monolayer at the air-water interface is described. It was seen that at the air-water interface chiral recognition was proven to be more strongly modulated than in solutions and a small difference in the amino acid structure resulted in differing selectivities.