Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B-null mice

Authors :: Choi, Young Hun
Park, Sunhee
Hockman, Steven
Zmuda-Trzebiatowska, Emilia
Svennelid, Fredrik
Haluzik, Martin
Gavrilova, Oksana
Ahmad, Faiyaz
Pepin, Laurent
Napolitano, Maria
Taira, Masato
Sundler, Frank
Holst, Lena Stenson
Degerman, Eva
Manganiello, Vincent C.
Source :: Journal of Clinical Investigation. Dec, 2006, Vol. 116 Issue 12, p3240, 12 p.
Publication Year :: 2006
Abstract: Cyclic nucleotide phosphodiesterase 3B (PDE3B) has been suggested to be critical for mediating insulin/IGF-1 inhibition of cAMP signaling in adipocytes, liver, and pancreatic [beta] cells. In Pde3b-KO adipocytes we found [...]

Subjects :: Homeostasis -- Research
Mice -- Research
Phosphodiesterases -- Research
Medical research
Medicine, Experimental

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