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Magainin oligomers reversibly dissipate delta mu H+ in cytochrome oxidase liposomes

Authors :
Juretic, Davor
Hendler, Richard W.
Kamp, Frits
Caughey, Winslow S.
Zasloff, Michael
Westerhoff, Hans V.
Source :
Biochemistry. April 19, 1994, Vol. 33 Issue 15, p4562, 9 p.
Publication Year :
1994

Abstract

Magainin peptides are antimicrobial material that reduces the membrane activity of cytochrome oxidase liposomes. Magainin disrupts respiratory control and is proportional to lipid concentration. Respiratory control is revived to normal by proteolytic digestion of magainin. Magainin modulates multimeric pore that is responsible for membrane permeability and causes ion permeation that enhances respiratory activities.

Details

ISSN :
00062960
Volume :
33
Issue :
15
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.15504529