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Precursors of the neurosteroids
- Source :
- Proceedings of the National Academy of Sciences of the United States. April 12, 1994, Vol. 91 Issue 8, p3220, 4 p.
- Publication Year :
- 1994
-
Abstract
- A study of organic solvent extracts of rat brains revealed certain labile constituents other than peroxides that behaved as precursors of neurosteroids pregnenolone and dehydropiandrosterone. These labile compounds, when treated with several reagents, formed two ketosteroids. FeSO4 facilitated the conversion of rat brain extract into the two neurosteroids.
- Subjects :
- Brain -- Histopathology
Steroids (Drugs) -- Analysis
Science and technology
Subjects
Details
- ISSN :
- 00278424
- Volume :
- 91
- Issue :
- 8
- Database :
- Gale General OneFile
- Journal :
- Proceedings of the National Academy of Sciences of the United States
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.15468661