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Effect of histamine on rat gastric H+-K+-ATPase alpha-subunit expression
- Source :
- The American Journal of Physiology. March, 1994, Vol. 266 Issue 3, pG444, 7 p.
- Publication Year :
- 1994
-
Abstract
- Studies on rat gastric H+-K+-ATPase alpha subunit reveal that H2 receptor activation leads to histamine stimulation of H+-K+-ATPase alpha subunit activity. Famotidine, which enhances gastric pH and serum gastrin, reduces the H2 receptor action. It also reduces the level of H+-K+-ATPase mRNA.
Details
- ISSN :
- 00029513
- Volume :
- 266
- Issue :
- 3
- Database :
- Gale General OneFile
- Journal :
- The American Journal of Physiology
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.15453897