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Discordance between thermogenic activity and expression of uncoupling protein in brown adipose tissue of old rats
- Source :
- Journals of Gerontology. March, 1994, Vol. 49 Issue 2, pB54, 6 p.
- Publication Year :
- 1994
-
Abstract
- A study of old rats reveals dissonance between uncoupling protein (UCP) expression and brown adipose tissue (BAT) thermogenic activity. This suggests that aging may be associated with failure during or after UCP translation, leading to impaired BAT thermogenic activity. Age-related changes in insulin receptor and glucose transporter-4 mRNA levels may also be involved in the process.
Details
- ISSN :
- 00221422
- Volume :
- 49
- Issue :
- 2
- Database :
- Gale General OneFile
- Journal :
- Journals of Gerontology
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.15368439