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The Brown Norway rat as a model of male reproductive aging: evidence for both primary and secondary testicular failure

Authors :
Gruenewald, David A.
Naai, Michael A.
Hess, David L.
Matsumoto, Alvin M.
Source :
Journals of Gerontology. March, 1994, Vol. 49 Issue 2, pB42, 9 p.
Publication Year :
1994

Abstract

The aging Brown Norway (BN) rat, which exhibits primary and secondary testicular failure but not reduced gonadotropin levels following steroid or prolactin secretion, is ideal to study male reproductive aging. This method of study will overcome the problems of progesterone secretion in male F344 rats, normally used to study male aging. The BN rats do not exhibit age-related increases in progesterone and estradiol.

Details

ISSN :
00221422
Volume :
49
Issue :
2
Database :
Gale General OneFile
Journal :
Journals of Gerontology
Publication Type :
Academic Journal
Accession number :
edsgcl.15368435