Influence of the membrane potential on the protonation of bacteriorhodopsin: Insights from electrostatic calculations into the regulation of proton pumping

Authors :: Bombarda, Elisa
Becker, Torsten
Ullmann, G. Matthias
Source :: Journal of the American Chemical Society. Sept 20, 2006, Vol. 128 Issue 37, p12129, 11 p.
Publication Year :: 2006
Abstract: A procedure is introduced to calculate the protonation probability of titratable sites of a membrane protein in the presence of a membrane potential. The proton pump bacteriorhodopsin is used as an example to show on a structural level how the membrane potential affects the energetics of the protonation of proteins.

Subjects :: Bacteriorhodopsin -- Chemical properties
Membrane proteins -- Research
Protons -- Research
Chemistry

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