[sup.19.F] NMR studies of the native and denatured states of green fluorescent protein

NMR studies on the native and denatured states of green fluorescent protein are presented, which gives vital information on the first and last states of protein on the folding pathway. The data suggest that pH-denatured and GdnDCI-denatured states are similar in terms of the chemical environments of the tyrosine residues.