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Drug-disease interactions: losartan effect is not downregulated by rheumatoid arthritis

Authors :
Daneshtalab, Noriko
Lewanczuk, Richard Z.
Russell, Anthony S.
Jamali, Fakhreddin
Source :
Journal of Clinical Pharmacology. November 2006, Vol. 46 Issue 11, p1344, 12 p.
Publication Year :
2006

Abstract

Inflammatory conditions, such as rheumatoid arthritis, reduce response to calcium channel and β-adrenergic antagonists but not the angiotensin II type 1 receptor ([AT.sub.1]R) antagonist valsartan. Inflammation also reduces clearance of [...]

Details

Language :
English
ISSN :
00912700
Volume :
46
Issue :
11
Database :
Gale General OneFile
Journal :
Journal of Clinical Pharmacology
Publication Type :
Academic Journal
Accession number :
edsgcl.152872114