Dynamic and 2D NMR studies on hydrogen-bonding aggregates of cholesterol in low-polarity organic solvents

The aggregate formation among cholesterol molecules is revealed by [sup.1.H] and [sup.2.H] NMR solution-state self-diffusion and 1dimensional and 2 dimensional measurements. Cholesterol forms aggregates in the organic solvents that mimic the membrane bilayer hydrophobic core as chloroform and cyclohexane but it does not in 1-octanol.