Lipopolysaccharides of Campylobacter jejuni serotype O:19: structure of O antigen chains from the serostrain and two bacterial isolates from patients with the Guillain-Barre syndrome

NMR spectroscopy and methylation linkage analysis reveal the presence of the O antigenic polysaccharide found in Campylobacter jejuni and bacterial isolates found in patients who later develop the Guillain-Barre syndrome. The glycan is a hyaluronic acid derivative with beta-D-glucuronic acid residues present as amides of 2-amino-2-deoxyglycerol. A similar structure is seen in Shigella boydii type 8 and Vibrio cholerae strain H11.