Embryonic expression of Lim-1, the mouse homolog of Xenopus XLim-1, suggests a role in lateral mesoderm differentiation and neurogenesis

Early mesoderm development and subsequent specification of a differentiated phenotype in subsets of cells of the mesonephrons and sensory neurons of the central nervous system involve the action of Lim-1, the mouse homolog of Xenopus Xlim-1. Nearly 85% identity over the entire protein and a high degree of identity with Xlim-1 in the LIM and homeodomains are evident for nucleotide and deduced amino acid sequences.