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Varenicline, an [alpha]4[beta]2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: A randomized controlled trial

Authors :
Gonzales, David
Rennard, Stephen I.
Nides, Mitchell
Williams, Kathryn E.
Reeves, Karen R.
Oncken, Cheryl
Gong, Jason
Azoulay, Salomon
Billing, Clare B.
Watsky, Eric J.
Source :
JAMA, The Journal of the American Medical Association. July 5, 2006, Vol. 296 Issue 1, p47, 9 p.
Publication Year :
2006

Abstract

A study was conducted to assess efficacy and safety of varenicline for smoking cessation compared with sustained-release bupropion (bupropion SR) and placebo. It was found that varenicline was significantly more efficient than placebo for smoking cessation at all time points and significantly more effective than bupropion SR at the end of 12 weeks of drug treatment and at 24 weeks.

Details

Language :
English
ISSN :
00987484
Volume :
296
Issue :
1
Database :
Gale General OneFile
Journal :
JAMA, The Journal of the American Medical Association
Publication Type :
Academic Journal
Accession number :
edsgcl.149327215