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Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors

Authors :
Lam, P.Y.S.
Jadhav, P.K.
Eyermann, C.J.
Hodge, C.N.
Ru, Y.
Bacheler, L.T.
Meek, J.L.
Otto, M.J.
Rayner, M.M.
Wong, Y.N.
Chang, C.H.
Weber, P.C.
Jackson, D.A.
Sharpe, T.R.
Ericksonviitanen, S.
Source :
AIDS Weekly. Feb 28, 1994, p25, 1 p.
Publication Year :
1994

Abstract

SOURCE: Science, January 21, 1994;263(5145):380-384. According to the authors' abstract of an article published in Science, "Mechanistic information and structure-based design methods have been used to design a series of [...]

Details

ISSN :
10691456
Database :
Gale General OneFile
Journal :
AIDS Weekly
Publication Type :
News
Accession number :
edsgcl.14852120