Mast cell IL-4 expression is regulated by Ikaros and influences encephalitogenic Th1 responses in EAE

Authors :: Gregory, Gregory D.
Raju, Shveta S.
Winandy, Susan
Brown, Melissa A.
Source :: Journal of Clinical Investigation. May, 2006, Vol. 116 Issue 5, p1327, 10 p.
Publication Year :: 2006
Abstract: When exposed to a pathogen, a naive [CD4.sup.+] T cell is forced to make a cell fate decision that leads to a polarized population of Th1 IFN-[gamma]- or Th2 IL-4--producing [...]

Subjects :: Gene expression -- Research
Mice -- Research
Mast cells -- Research
T cells -- Research
Medical research
Medicine, Experimental

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