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Spare guanylyl cyclase NO receptors ensure high no sensitivity in the vascular system

Authors :
Mergia, Evanthia
Friebe, Andreas
Dangel, Oliver
Russwurm, Michael
Koesling, Doris
Source :
Journal of Clinical Investigation. June, 2006, Vol. 116 Issue 6, p1731, 7 p.
Publication Year :
2006

Abstract

In the vascular system, the receptor for the signaling molecule NO, guanylyl cyclase (GC), mediates smooth muscle relaxation and inhibition of platelet aggregation by increasing intracellular cyclic GMP (cGMP) concentration. [...]

Details

Language :
English
ISSN :
00219738
Volume :
116
Issue :
6
Database :
Gale General OneFile
Journal :
Journal of Clinical Investigation
Publication Type :
Academic Journal
Accession number :
edsgcl.147669188