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An antibody-deficiency syndrome due to mutations in the CD19 gene
- Source :
- The New England Journal of Medicine. May 4, 2006, Vol. 354 Issue 18, p1901, 2 p.
- Publication Year :
- 2006
-
Abstract
- Four patients from two unrelated families who had increased susceptibility to infection, hypogammaglobulinemia, and normal numbers of B cells are evaluated. Results indicate that mutation of the CD19 gene causes a type of hypogammaglobulinemia in which the response of mature B cells to antigenic stimulations is defective.
Details
- Language :
- English
- ISSN :
- 00284793
- Volume :
- 354
- Issue :
- 18
- Database :
- Gale General OneFile
- Journal :
- The New England Journal of Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.146564538