Phosphatidylinositol-4,5-biphosphate (PIP2) differentially regulates the interaction of human erythrocyte protein 4.1 (4.1R) with membrane proteins

Authors :: Xiuli An
Xihui Zhang
Debnath, Gargi
Baines, Anthony J.
Mohandas, Narla
Source :: Biochemistry. May 9, 2006, Vol. 45 Issue 18, p5725, 8 p.
Publication Year :: 2006
Abstract: The interaction of human erythrocyte protein 4.1 (4.1R) with phosphatidylinositol-4,5-bisphosphate (PIP2) and the effect of PIP2 on the interaction of 4.1R with membrane proteins are characterized and assessed. The results have shown that PIP2 is a major, selective regulatory cofactor in red cell membrane-cytoskeletal interactions.

Subjects :: Phosphatidylinositol -- Chemical properties
Diphosphonates -- Chemical properties
Erythrocytes -- Research
Cell membranes -- Research
Biological sciences
Chemistry

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