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Nuclear receptors in lipid metabolism: Targeting the heart of dyslipidemia

Authors :
Beaven, Simon W.
Tontonoz, Peter
Source :
Annual Review of Medicine. Annual, 2006, Vol. 57, 313-329
Publication Year :
2006

Abstract

A study was conducted on the important role played by nuclear hormone receptors in lipid and inflammatory homeostasis, which forms the basis for future therapies. Results show that the liver X receptor (LXR) and peroxisome proliferator-activated receptor (PPAR) are made attractive molecular targets for managing lipid-related diseases as a result of glucose homeostasis and inflammation.

Details

Language :
English
ISSN :
00664219
Volume :
57
Database :
Gale General OneFile
Journal :
Annual Review of Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.145760271