Influence of fluorescent probe size and cytochrome b5 on drug-drug interactions in CYP2C9

Authors :: Hummel, Matthew A.
Tracy, Timothy S.
Hutzler, J. Matthew
Wahlstrom, Jan L.
Zhou, Yihong
Rock, Dan A.
Source :: Journal of Biomolecular Screening. April 2006, Vol. 11 Issue 3, p303, 7 p.
Publication Year :: 2006
Abstract: 7-Methoxy-4-trifluoromethylcoumarin (MFC) has been used extensively in high-throughput screens for the identification of potential CYP2C9 interactions. More recently, additional probes from Invitrogen have been used. Vivid 2C9 Green is the [...]

Subjects :: Drug interactions -- Research
Pharmaceutical research -- Research
Cytochromes -- Research
Biological sciences
Research

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