Lewis base activation of Lewis acids: Vinylogous aldol addition reactions of conjugated N, O-silyl ketene acetals to aldehydes

Authors :: Denmark, Scott E.
Heemstra, John R., Jr.
Source :: Journal of the American Chemical Society. Feb 1, 2006, Vol. 128 Issue 4, 1038-1039
Publication Year :: 2006
Abstract: The potent biological activity and structural diversity of the polyketide class of natural products are studied. In the preliminary survey of structural generality ketene acetals bearing methyl groups on the alpha and beta atoms of the dienyl unit are prepared.

Subjects :: Acylation -- Analysis
Aldehydes -- Structure
Aldehydes -- Chemical properties
Lewis structures -- Usage
Polyketides -- Structure
Polyketides -- Chemical properties
Chemistry

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