DNA-binding studies of Cu(bcp)(sub 2)(super +) and Cu(dmp)(sub 2)(super +): DNA elongation without intercalation of Cu(bcp)(sub 2)(super +)

A research on the ways by which copper phenanthroline bind to beta-form DNA involved the varying of the composition of the DNA, and the use of poly (dG-dC).poly (dG-dC), M. lysodeikticus DNA, salmon testes DNA and poly (dA-dT).poly (dA-dT) as hosts. The dmp complex bound externally in a solvent accessible site was discovered. The presence of DNA causes Cu(bcp)2+ to be emissive. Hence, the metal center is accessible to the solvent.