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Allosteric control of oligonucleotide hybridization by metal-induced cyclization
- Source :
- Journal of the American Chemical Society. Dec 28, 2005, Vol. 127 Issue 51, 18016-18017
- Publication Year :
- 2005
-
Abstract
- A stable, single-stranded DNA circle is smoothly formed from a linear precursor by metal Fe(sub 2+) assisted ring closure. With metal Zn(sub 2+), cyclization is reversible and a novel, complex type of allosteric regulation of hybridization is observed.
- Subjects :
- Ring formation (Chemistry) -- Research
Nucleotides -- Research
Chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 00027863
- Volume :
- 127
- Issue :
- 51
- Database :
- Gale General OneFile
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.144073483