Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog

Authors :: Heeger, Sebastian
Leismann, Oliver
Schittenhelm, Ralf
Schraidt, Oliver
Heidmann, Stefan
Lehner, Christian F.
Source :: Genes & Development. Sept 1, 2005, Vol. 19 Issue 17, 2041-2053
Publication Year :: 2005
Abstract: Study is conducted in which a genetic loci is screened that modify the aberrant phenotypes caused by over expression of regulatory separase complex subunits Pimples/securin and Three rows in Drosophila. An interacting gene is found to encode a constitutive centromere protein.

Subjects :: Centromeres -- Structure
Centromeres -- Identification and classification
Drosophila -- Genetic aspects
Drosophila -- Physiological aspects
Fluorescent antibody technique -- Analysis
Immunofluorescence -- Analysis
Gene mutations -- Analysis
Biological sciences

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