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Binding of amyloidogenic transthyretin to the plasma membrane alters membrane fluidity and induces neurotoxicity
- Source :
- Biochemistry. August 30, 2005, Vol. 44 Issue 34, 11618-11627
- Publication Year :
- 2005
-
Abstract
- The mechanism of transthyretin (TTR) amyloid neurotoxicity on SH-SY5Y neuroblastoma cells is examined. The results reveal that the TTR can bind to the plasma membrane and cause a change in membrane fluidity.
Details
- Language :
- English
- ISSN :
- 00062960
- Volume :
- 44
- Issue :
- 34
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.143502851