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Molecular organization of Leishmania RNA virus 1

Authors :
Stuart, Kenneth D.
Weeks, Reitha
Guilbride, Lys
Myler, Peter J.
Source :
Proceedings of the National Academy of Sciences of the United States. Sept 15, 1992, Vol. 89 Issue 18, p8596, 5 p.
Publication Year :
1992

Abstract

A study of the complete nucleotide sequence of the double-stranded RNA genome of the Leishmania RNA virus showed three open reading frames. Examination of the reading frames showed a plus one translational frameshift which produces a gag-pol type of fusion protein. It was further shown that the first open reading frame does not encode protein but initiates translation and or RNA stability.

Details

ISSN :
00278424
Volume :
89
Issue :
18
Database :
Gale General OneFile
Journal :
Proceedings of the National Academy of Sciences of the United States
Publication Type :
Academic Journal
Accession number :
edsgcl.14323658