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Fragmentation of proteins in the 13- to 29-kDa mass range observed by (super 252)Cf-plasma desorption mass spectrometry
- Source :
- Proceedings of the National Academy of Sciences of the United States. July 1, 1992, Vol. 89 Issue 13, p6215, 5 p.
- Publication Year :
- 1992
-
Abstract
- Cf-plasma desorption mass spectrometry (PDMS) was used to study the fragmentation of ribonuclease A, papain and proteinase K, all of which are within the 13- to 29-kDa mass range. The results showed that the plasma desorption process could induce efficient, sequence-specific fragmentation of large, native proteins. The procedure could be used as a starting step in the sequence determination of large protein molecules.
Details
- ISSN :
- 00278424
- Volume :
- 89
- Issue :
- 13
- Database :
- Gale General OneFile
- Journal :
- Proceedings of the National Academy of Sciences of the United States
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.14258036