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Stem cell function, self-renewal, and behavioral heterogeneity of cells from the adult muscle satellite cell niche

Authors :
Collins, Charlotte A.
Olsen, Irwin
Zammit, Peter S.
Heslop, Louise
Petrie, Aviva
Partridge, Terence A.
Morgan, Jennifer E.
Source :
Cell. July 29, 2005, Vol. 122 Issue 2, p289, 13 p.
Publication Year :
2005

Abstract

Single intact myofibers are transplanted into radiation-ablated muscles to demonstrate that satellite cells are self-sufficient as a source of regeneration. The transplanted satellite cells vigorously self-renew expanding in number and repopulating the host muscle with new satellite cells.

Details

Language :
English
ISSN :
00928674
Volume :
122
Issue :
2
Database :
Gale General OneFile
Journal :
Cell
Publication Type :
Academic Journal
Accession number :
edsgcl.141653092