Correlation of tryptophan fluorescence intensity decay parameters with 1H NMR-determined rotamer conformations: (tryptophan2)oxytocin

The fluorescence properties of (tryptophan2)oxytocin were studied using intensity decay parameters and 1H NMR results. It was shown that results of fluorescence studies using a tryptophan analogue are compatible with the rotamer model of (Tyr2)oxytocin. The X2 conformers of the tryptophan analogue do not significantly affect fluorescence decay kinetics and three decay constants can be found in the three X1 rotamers of tryptophan.