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Repair of O-6-methylguanine in rat pancreatic beta-cells after exposure to N-methyl-N-nitrosourea

Authors :
Nelson, J. Wesley
Ledoux, Susan P.
Wilson, Glenn L.
Source :
Diabetes. August 1993, Vol. 42 Issue 8, p1187, 8 p.
Publication Year :
1993

Abstract

Because of the possible involvement of [O.sup.6]-methyldeoxyguanosine as a cytotoxic and carcinogenic lesion in pancreatic β-cells, studies were undertaken to assess the ability of rat β-cells to repair this DNA [...]

Details

Language :
English
ISSN :
00121797
Volume :
42
Issue :
8
Database :
Gale General OneFile
Journal :
Diabetes
Publication Type :
Periodical
Accession number :
edsgcl.14105883