Effect of the MDR1 C3435T variant and P-glycoprotein induction on dicloxacillin pharmacokinetics

Authors :: Putnam, Wendy S.
Woo, Jonathan M.
Huang, Yong
Benet, Leslie Z.
Source :: Journal of Clinical Pharmacology. April 2005, Vol. 45 Issue 4, p411, 11 p.
Publication Year :: 2005
Abstract: This study investigated 2 hypotheses about genotype-phenotype relationships for the efflux transporter, P-glycoprotein: (1) the presence of a synonymous C3435T variant in exon 26 of the MDR1 gene correlates to [...]

Subjects :: Glycoproteins -- Health aspects -- Research
Pharmacokinetics -- Research -- Health aspects
Dicloxacillin -- Health aspects -- Research
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