Multiplexed G-protein-coupled receptor [Ca.sup.2+] flux assays for high-throughput screening

Authors :: Miret, Juan J.
Zhang, Jiansu
Min, Hyunsuk
Lewis, Karina
Roth, Mark
Charlton, Maura
Bauer, Paul H.
Source :: Journal of Biomolecular Screening. December 2005, Vol. 10 Issue 8, p780, 8 p.
Publication Year :: 2005
Abstract: An early drug discovery approach focusing on gene families can benefit from strategies that exploit common signaling mechanisms to more effectively identify and characterize novel chemical lead structures. Multiplexing, defined [...]

Subjects :: Structure
Genetic aspects
Product development
Calcium (Chemical element) -- Structure -- Product development
G proteins -- Genetic aspects
Pharmaceutical industry -- Product development
Calcium -- Structure -- Product development

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