Stereoselective synthesis of 3-alkylideneoxindoles via palladium-catalyzed domino reactions

A study develops efficient catalytic methods for the stereoselective and diversity synthesis of various (E)-, (Z)-, and disubstituted 3-alkylideneoxindoles and 3-alkylidenebenzofuran-2-ones via palladium-catalyzed domino reactions. The method provides a versatile tool for further synthesis of natural products and random screening in the search for drug candidates.