Back to Search Start Over

Binding of madindoline A to the extracellular domain of gp130

Authors :
Saleh, Abu Z.M.
Greenman, Kevin L.
Billings, Susan
Van Vranken, David L.
Krolewski, John J.
Source :
Biochemistry. August 16, 2005, Vol. 44 Issue 32, p10822, 6 p.
Publication Year :
2005

Abstract

The binding of madindoline A (Mad A) to gp130 is specific and noncovalent and displays a relatively low affinity. It is shown that the tricyclic 3a-hydroxytetrahydrofuro[2,3-b]indole (HFI) moiety of MadA alone is not sufficient for binding.

Subjects

Subjects :
Extracellular fluid -- Research
Indole -- Research
Protein research
Biological sciences
Chemistry

Details

Language :
English
ISSN :
00062960
Volume :
44
Issue :
32
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.139771091

Tools

Authors Abstract Subjects Details