A flexible and versatile strategy for covalent immobilization of chiral catalysts based on pyridinebis(oxaline) ligands

The introduction of the substituents in position 4 of the pyridine ring is a flexible and versatile strategy for the immobilization of chiral pybox ligands. This strategy allows complete modulation of the final chiral catalyst in different ways, including the structure of the support, the length of the spacer, and the electronic properties of the ligand.