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Expression cloning of the murine and human interleukin 9 receptor cDNAs

Authors :
Renauld, Jean-Christophe
Druez, Catherine
Kermouni, Abdenaim
Houssiau, Frederic
Uyttenhove, Catherine
Roost, Emiel van
Snick, Jacques van
Source :
Proceedings of the National Academy of Sciences of the United States. June 15, 1992, Vol. 89 Issue 12, p5690, 5 p.
Publication Year :
1992

Abstract

The cDNA coding for the murine interleukin-9 (IL-9) receptor was expressed in COS cells and characterized. Analysis of the 52-kDa protein showed the presence of a typical membrane-spanning domain and a putative signal peptide. Sequence analysis showed that the IL-9 receptor is highly similar to the hematopoietin receptor superfamily. Furthermore, this receptor is expressed in both membrane-bound and soluble forms.

Details

ISSN :
00278424
Volume :
89
Issue :
12
Database :
Gale General OneFile
Journal :
Proceedings of the National Academy of Sciences of the United States
Publication Type :
Academic Journal
Accession number :
edsgcl.13599168