A conserved retina-specific gene encodes a basic motiff/leucine zipper domain

Authors :: Swaroop, Anand
Junzhe Xu
Pawar, Hemant
Jackson, Anne
Skolnick, Craig
Agarwal, Neeraj
Source :: Proceedings of the National Academy of Sciences of the United States. Jan 1, 1992, Vol. 89 Issue 1, p266, 5 p.
Publication Year :: 1992
Abstract: A human cDNA which was exclusively expressed in neural retina and encoded a polypeptide of the jun and fos oncoprotein was isolated and identified. This cDNA was designated as AS321 and was highly expressed in photoreceptors. Sequential analysis of its polypeptides showed a similar phosphorylation sites for protein kinase A and proline-directed protein kinase. The C-terminal segment of AS321 carried a basic and leucine zipper domain exhibited by DNA binding proteins of the jun and fos oncoprotein family. The gene was suggested to be named as gene NRL for neural retina leucine zipper.

Subjects :: Retina -- Research
Oncogenes -- Research
DNA binding proteins -- Research
Cloning -- Research
Science and technology

ISSN :: 00278424
Volume :: 89
Issue :: 1
Database :: Gale General OneFile
Journal :: Proceedings of the National Academy of Sciences of the United States
Publication Type :: Academic Journal
Accession number :: edsgcl.13595080

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