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Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
- Source :
- Biochemistry. May 10, 2005, Vol. 44 Issue 18, 6823-6830
- Publication Year :
- 2005
-
Abstract
- A study was carried out on a series of mutants of chymotrypsin inhibitor 2 (Cl2) to determine their relative importance for inhibition of the serine protease subtilisin BPN', and for resistance of the inhibitor to proteolysis. The above-mentioned properties were investigated in tandem with the crystal structure of the mutant inhibitor-enzyme complexes
Details
- Language :
- English
- ISSN :
- 00062960
- Volume :
- 44
- Issue :
- 18
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.135773778