Instability of the minisatellite sequence in the first intron of the rat renin gene and localization of the gene to chromosome 13q13 between FH and PEPC loci

A study was done on the minisatellite sequence in the first intron of the rat renin gene. A genetic instability was shown in the minisatellite of a new allelic variant found after testing 136 animals from two sets of backcross progenies. Renin locus on linkage group X was identified between fumarate hydrase and peptidase loci. The renin gene on the rat chromosome was then mapped using fluorescence in situ hybridization.