Highly multiplexed molecular inversion probe genotyping: Over 10,000 targeted SNPs genotyped in a single tube assay

A study was conducted which reported the development of molecular inversion probe technology with four-color, single array detection, applied to large-scale genotyping of up to 12,000 SNPs per reaction. Results of the study demonstrate the suitability of the technology for comprehensive association studies that use targeted SNPs in indirect linkage disequilibrium studies or that directly look for causative mutations.